Vadim J. Gurvich, PhD, MBA

Research Associate Professor, Department of Medicinal Chemistry

Vadim J. Gurvich

Contact Info

Office Phone 612-626-5294

Fax 612-626-6862

Office Address:
717 Delaware St SE, Room 487

Mailing Address:
Institute for Therapeutics Discovery & Development (ITDD)
717 Delaware Street SE
Room 451
Minneapolis, Minnesota 55414

Research Associate Professor, Department of Medicinal Chemistry

Associate Director, ITDD; Director, Chemical Process Development, Institute for Therapeutics Discovery and Development (ITDD)

PhD, Hebrew University of Jerusalem, 1996

MBA, University of Kansas, 2003

MS, Mendeleev University of Chemical Technology, 1987


Research Summary/Interests

  • Drug discovery
  • Drug synthesis
  • Drug development
  • Synthetic organic and medicinal chemistry


  • Benyumov, A.; Gurvich, V.J.; Lis, L. G.; Williams, B.W.; Kirstein, M.N. Combinatorial pharmacologic effects for gemcitabine and metabolite dFdU. ChemMedChem 2011, 6, 457-464.
  • Rangwala, H.S.; Giraldes, J.W.; Gurvich, V.J. Synthesis and purification of [2-13C]-5-Fluorouracil. J. Label. Compd. Radiopharm. 2011, 54(6), 340-3.
  • Lis L.G.; Smart, M.A.; Luchniak, A.; Gupta, M.L.; Gurvich, V.J. Synthesis and biological evaluation of a biotinylated paclitaxel with an extra-long chain spacer arm. Med. Chem. Lett. 2012, 3, 745-8.
  • Stenland, C.J.; Lis, L. G.; Schendel, F. J.; Hahn, N. J.; Smart, M.A.; Miller, A.L.; von Keitz, M.G.; Gurvich, V.J. A Practical and Scalable Manufacturing Process for an Antifungal Agent, Nikkomycin Z. Organic Process Research & Development 2013, 17, 265-272.
  • Gurvich, V.J.; Byrn, S.R. NIPTE: a multi-university partnership supporting academic drug development. Drug Discovery Today 2013, 18, 916-921.
  • Khatri, A.; Williams, B.W.; Fisher, J.; Brundage, R.C.; Gurvich, V.J.; Lis, L.G.; Skubitz, K.M.; Dudek, A.Z.; Greeno, E.W.; Kratzke, R.A.; Lamba, J.K.; Kirstein, M.N. SLC28A3 genotype and gemcitabine rate of infusion affect dFdCTP metabolite disposition in patients with solid tumours. Br. J. Cancer 2014, 110, 304-312.
  • Dosa, P.I.; Georg, G.I.; Gurvich, V.J.; Hawkinson, J.E.; Walters, M.A.; Wong, H.L. From HTS to Phase I: The Institute for Therapeutics Discovery and Development at the University of Minnesota. Comb. Chem. High Throughput Screening 2014, 17, 231-240.