Jon Hawkinson Received NIH Shared Instrumentation Award
October 10, 2016
Jon Hawkinson, director of the ITDD High-throughput Screening Laboratory, received a $343,887 NIH shared instrumentation award for the plasmon resonance (SPR) instrument, which will allow researchers at the U of M to directly determine the affinity ofantibodies and small molecule probes and drugs for receptors, and to measure protein-protein interactions. The exquisite sensitivity of this SPR instrument will allow the detection of very small mass changes in small molecule drug discovery applications, such as fragment-based screening. This instrument will directly impact research in diverse therapeutic areas, including contraception, anti-infectives, metabolic disease, neuroscience, and cancer, as well as basic biology research.
Major User Group Members are:
Gunda Georg Medicinal Chemistry
Courtney Aldrich Medicinal Chemistry
Daniel Harki Medicinal Chemistry
Dave Bernlohr Biochemistry, Molecular Biology, and Biophysics
Anja Bielinsky Biochemistry, Molecular Biology, and Biophysics
Li-Na Wei Pharmacology
Ameeta Kelekar Laboratory Medicine and Pathology
Masato Yamamoto Surgery