Purification and Analytical Compounding Services

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purification and analytical compounding

The ITDD Purification and Analytical Services Facility carries out a variety of small-molecule analyses and purifications on a regular basis including LC-MS, low resolution mass spectrometry (LRMS), preparative, reverse phase liquid chromatography, and NMR. These analyses are facilitated by on-site instruments that include a Waters UPLC, two Waters ZQ mass spectrometers, a Waters autopurification system, and a Bruker 400 MHz NMR spectrometer.

Services

Services

Services

  • Low-resolution mass spectrometry
  • UPLC-MS
  • Reverse-phase, preparative separations
  • NMR experiments (1H, 13C, others)
  • Compound plating and dispensing
  • Vial weighing

Additional Analytical Equipment

Additional Analytical Equipment

  • Autopol V Polarimeter
  • Perkin-Elmer IR Spectrophotometer
  • 785 Karl Fisher Titrino System

Core Capabilities

Core Capabilities

  • 400 MHz Bruker NMR
  • Autopol V Polarimeter
  • Waters Acquity uPLC with ZQ mass spectrometer
  • Waters Autopurification system with ZQ mass spectrometer
  • Perkin-Elmer IR Spectrophotometer
  • Waters Preparative and Analytical HPLC
  • 785 Karl Fischer Titrino System

Contact

Dr. Michael A. Walters, Director, Lead and Probe Discovery
walte294@umn.edu

Telephone: 612-624-4728
Fax: 612-626-6862